Risk of Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis in Patients With Acute Ischemic Stroke and High Cerebral Microbleed Burden: A Meta-analysis.
Identifieur interne : 001788 ( Main/Exploration ); précédent : 001787; suivant : 001789Risk of Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis in Patients With Acute Ischemic Stroke and High Cerebral Microbleed Burden: A Meta-analysis.
Auteurs : Georgios Tsivgoulis ; Ramin Zand ; Aristeidis H. Katsanos [Grèce] ; Guillaume Turc [France] ; Christian H. Nolte [Allemagne] ; Simon Jung [Suisse] ; Charlotte Cordonnier [France] ; Jochen B. Fiebach [Allemagne] ; Jan F. Scheitz [Allemagne] ; Pascal P. Klinger-Gratz [Suisse] ; Catherine Oppenheim [France] ; Nitin Goyal ; Apostolos Safouris [Grèce] ; Heinrich P. Mattle [Suisse] ; Anne W. Alexandrov [Australie] ; Peter D. Schellinger [Allemagne] ; Andrei V. AlexandrovSource :
- JAMA neurology [ 2168-6157 ] ; 2016.
Descripteurs français
- KwdFr :
- Accident vasculaire cérébral (imagerie diagnostique), Accident vasculaire cérébral (traitement médicamenteux), Accident vasculaire cérébral (étiologie), Administration par voie intraveineuse, Bases de données bibliographiques (), Encéphalopathie ischémique (), Encéphalopathie ischémique (imagerie diagnostique), Facteurs de risque, Fibrinolytiques (effets indésirables), Humains, Hémorragie cérébrale (), Hémorragie cérébrale (imagerie diagnostique), Hémorragie cérébrale (épidémiologie), Imagerie par résonance magnétique.
- MESH :
- effets indésirables : Fibrinolytiques.
- imagerie diagnostique : Accident vasculaire cérébral, Encéphalopathie ischémique, Hémorragie cérébrale.
- traitement médicamenteux : Accident vasculaire cérébral.
- épidémiologie : Hémorragie cérébrale.
- étiologie : Accident vasculaire cérébral.
- Administration par voie intraveineuse, Bases de données bibliographiques, Encéphalopathie ischémique, Facteurs de risque, Humains, Hémorragie cérébrale, Imagerie par résonance magnétique.
English descriptors
- KwdEn :
- Administration, Intravenous, Brain Ischemia (complications), Brain Ischemia (diagnostic imaging), Cerebral Hemorrhage (chemically induced), Cerebral Hemorrhage (diagnostic imaging), Cerebral Hemorrhage (epidemiology), Databases, Bibliographic (statistics & numerical data), Fibrinolytic Agents (adverse effects), Humans, Magnetic Resonance Imaging, Risk Factors, Stroke (diagnostic imaging), Stroke (drug therapy), Stroke (etiology).
- MESH :
- chemical , adverse effects : Fibrinolytic Agents.
- chemically induced : Cerebral Hemorrhage.
- complications : Brain Ischemia.
- diagnostic imaging : Brain Ischemia, Cerebral Hemorrhage, Stroke.
- drug therapy : Stroke.
- epidemiology : Cerebral Hemorrhage.
- etiology : Stroke.
- statistics & numerical data : Databases, Bibliographic.
- Administration, Intravenous, Humans, Magnetic Resonance Imaging, Risk Factors.
Abstract
Cerebral microbleeds (CMBs) have been established as an independent predictor of cerebral bleeding. There are contradictory data regarding the potential association of CMB burden with the risk of symptomatic intracerebral hemorrhage (sICH) in patients with acute ischemic stroke (AIS) treated with intravenous thrombolysis (IVT).
DOI: 10.1001/jamaneurol.2016.0292
PubMed: 27088650
Affiliations:
- Allemagne, Australie, France, Grèce, Suisse
- Berlin, Canton de Berne, Hauts-de-France, Nord-Pas-de-Calais, Nouvelle-Galles du Sud, Île-de-France
- Berlin, Berne, Lille, Paris, Sydney
- Université Paris-Descartes
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Le document en format XML
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Schellinger</name><affiliation wicri:level="1"><nlm:affiliation>Departments of Neurology and Neurogeriatry, Johannes Wesling Medical Center, Minden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Departments of Neurology and Neurogeriatry, Johannes Wesling Medical Center, Minden</wicri:regionArea><wicri:noRegion>Minden</wicri:noRegion><wicri:noRegion>Minden</wicri:noRegion><wicri:noRegion>Minden</wicri:noRegion></affiliation></author><author><name sortKey="Alexandrov, Andrei V" sort="Alexandrov, Andrei V" uniqKey="Alexandrov A" first="Andrei V" last="Alexandrov">Andrei V. 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Katsanos</name><affiliation wicri:level="1"><nlm:affiliation>Second Department of Neurology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece4Department of Neurology, University of Ioannina School of Medicine, Ioannina, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Second Department of Neurology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece4Department of Neurology, University of Ioannina School of Medicine, Ioannina</wicri:regionArea><wicri:noRegion>Ioannina</wicri:noRegion></affiliation></author><author><name sortKey="Turc, Guillaume" sort="Turc, Guillaume" uniqKey="Turc G" first="Guillaume" last="Turc">Guillaume Turc</name><affiliation wicri:level="4"><nlm:affiliation>Department of Neurology, Hôpital Sainte-Anne, Université Paris Descartes, Sorbonne Paris Cité, Inserm UMR S894, Départements Hospitalo-Universitaires Neurovasc, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Neurology, Hôpital Sainte-Anne, Université Paris Descartes, Sorbonne Paris Cité, Inserm UMR S894, Départements Hospitalo-Universitaires Neurovasc, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation></author><author><name sortKey="Nolte, Christian H" sort="Nolte, Christian H" uniqKey="Nolte C" first="Christian H" last="Nolte">Christian H. Nolte</name><affiliation wicri:level="3"><nlm:affiliation>Klinik und Hochschulambulanz für Neurologie and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik und Hochschulambulanz für Neurologie and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Jung, Simon" sort="Jung, Simon" uniqKey="Jung S" first="Simon" last="Jung">Simon Jung</name><affiliation wicri:level="3"><nlm:affiliation>Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland8Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland8Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Cordonnier, Charlotte" sort="Cordonnier, Charlotte" uniqKey="Cordonnier C" first="Charlotte" last="Cordonnier">Charlotte Cordonnier</name><affiliation wicri:level="3"><nlm:affiliation>University Lille, Inserm, Centre Hospitalier Régional Universitaire de Lille, U1171, Degenerative and Vascular Cognitive Disorders, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University Lille, Inserm, Centre Hospitalier Régional Universitaire de Lille, U1171, Degenerative and Vascular Cognitive Disorders, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Fiebach, Jochen B" sort="Fiebach, Jochen B" uniqKey="Fiebach J" first="Jochen B" last="Fiebach">Jochen B. Fiebach</name><affiliation wicri:level="3"><nlm:affiliation>Klinik und Hochschulambulanz für Neurologie and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik und Hochschulambulanz für Neurologie and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Scheitz, Jan F" sort="Scheitz, Jan F" uniqKey="Scheitz J" first="Jan F" last="Scheitz">Jan F. Scheitz</name><affiliation wicri:level="3"><nlm:affiliation>Klinik und Hochschulambulanz für Neurologie and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik und Hochschulambulanz für Neurologie and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Klinger Gratz, Pascal P" sort="Klinger Gratz, Pascal P" uniqKey="Klinger Gratz P" first="Pascal P" last="Klinger-Gratz">Pascal P. Klinger-Gratz</name><affiliation wicri:level="3"><nlm:affiliation>Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, University of Bern, Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Oppenheim, Catherine" sort="Oppenheim, Catherine" uniqKey="Oppenheim C" first="Catherine" last="Oppenheim">Catherine Oppenheim</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiology, Hôpital Sainte-Anne, Université Paris Descartes, Sorbonne Paris Cité, Inserm UMR S894, Départements Hospitalo-Universitaires Neurovasc, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiology, Hôpital Sainte-Anne, Université Paris Descartes, Sorbonne Paris Cité, Inserm UMR S894, Départements Hospitalo-Universitaires Neurovasc, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation></author><author><name sortKey="Goyal, Nitin" sort="Goyal, Nitin" uniqKey="Goyal N" first="Nitin" last="Goyal">Nitin Goyal</name><affiliation><nlm:affiliation>Department of Neurology, The University of Tennessee Health Science Center, Memphis.</nlm:affiliation><wicri:noCountry code="subField">Memphis</wicri:noCountry></affiliation></author><author><name sortKey="Safouris, Apostolos" sort="Safouris, Apostolos" uniqKey="Safouris A" first="Apostolos" last="Safouris">Apostolos Safouris</name><affiliation wicri:level="1"><nlm:affiliation>Second Department of Neurology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece11Acute Stroke Unit, Metropolitan Hospital, Piraeus, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Second Department of Neurology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece11Acute Stroke Unit, Metropolitan Hospital, Piraeus</wicri:regionArea><wicri:noRegion>Piraeus</wicri:noRegion></affiliation></author><author><name sortKey="Mattle, Heinrich P" sort="Mattle, Heinrich P" uniqKey="Mattle H" first="Heinrich P" last="Mattle">Heinrich P. Mattle</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neurology, Inselspital, University Hospital Bern, University of Bern, Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Alexandrov, Anne W" sort="Alexandrov, Anne W" uniqKey="Alexandrov A" first="Anne W" last="Alexandrov">Anne W. Alexandrov</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, The University of Tennessee Health Science Center, Memphis12Australian Catholic University, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, The University of Tennessee Health Science Center, Memphis12Australian Catholic University, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Schellinger, Peter D" sort="Schellinger, Peter D" uniqKey="Schellinger P" first="Peter D" last="Schellinger">Peter D. Schellinger</name><affiliation wicri:level="1"><nlm:affiliation>Departments of Neurology and Neurogeriatry, Johannes Wesling Medical Center, Minden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Departments of Neurology and Neurogeriatry, Johannes Wesling Medical Center, Minden</wicri:regionArea><wicri:noRegion>Minden</wicri:noRegion><wicri:noRegion>Minden</wicri:noRegion><wicri:noRegion>Minden</wicri:noRegion></affiliation></author><author><name sortKey="Alexandrov, Andrei V" sort="Alexandrov, Andrei V" uniqKey="Alexandrov A" first="Andrei V" last="Alexandrov">Andrei V. Alexandrov</name><affiliation><nlm:affiliation>Department of Neurology, The University of Tennessee Health Science Center, Memphis.</nlm:affiliation><wicri:noCountry code="subField">Memphis</wicri:noCountry></affiliation></author></analytic><series><title level="j">JAMA neurology</title><idno type="eISSN">2168-6157</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Intravenous</term><term>Brain Ischemia (complications)</term><term>Brain Ischemia (diagnostic imaging)</term><term>Cerebral Hemorrhage (chemically induced)</term><term>Cerebral Hemorrhage (diagnostic imaging)</term><term>Cerebral Hemorrhage (epidemiology)</term><term>Databases, Bibliographic (statistics & numerical data)</term><term>Fibrinolytic Agents (adverse effects)</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Risk Factors</term><term>Stroke (diagnostic imaging)</term><term>Stroke (drug therapy)</term><term>Stroke (etiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Accident vasculaire cérébral (imagerie diagnostique)</term><term>Accident vasculaire cérébral (traitement médicamenteux)</term><term>Accident vasculaire cérébral (étiologie)</term><term>Administration par voie intraveineuse</term><term>Bases de données bibliographiques ()</term><term>Encéphalopathie ischémique ()</term><term>Encéphalopathie ischémique (imagerie diagnostique)</term><term>Facteurs de risque</term><term>Fibrinolytiques (effets indésirables)</term><term>Humains</term><term>Hémorragie cérébrale ()</term><term>Hémorragie cérébrale (imagerie diagnostique)</term><term>Hémorragie cérébrale (épidémiologie)</term><term>Imagerie par résonance magnétique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Fibrinolytic Agents</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Cerebral Hemorrhage</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Brain Ischemia</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Brain Ischemia</term><term>Cerebral Hemorrhage</term><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Fibrinolytiques</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cerebral Hemorrhage</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Stroke</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Accident vasculaire cérébral</term><term>Encéphalopathie ischémique</term><term>Hémorragie cérébrale</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Databases, Bibliographic</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Accident vasculaire cérébral</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Hémorragie cérébrale</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Accident vasculaire cérébral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Intravenous</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Risk Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie intraveineuse</term><term>Bases de données bibliographiques</term><term>Encéphalopathie ischémique</term><term>Facteurs de risque</term><term>Humains</term><term>Hémorragie cérébrale</term><term>Imagerie par résonance magnétique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cerebral microbleeds (CMBs) have been established as an independent predictor of cerebral bleeding. There are contradictory data regarding the potential association of CMB burden with the risk of symptomatic intracerebral hemorrhage (sICH) in patients with acute ischemic stroke (AIS) treated with intravenous thrombolysis (IVT).</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>France</li><li>Grèce</li><li>Suisse</li></country><region><li>Berlin</li><li>Canton de Berne</li><li>Hauts-de-France</li><li>Nord-Pas-de-Calais</li><li>Nouvelle-Galles du Sud</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Berne</li><li>Lille</li><li>Paris</li><li>Sydney</li></settlement><orgName><li>Université Paris-Descartes</li></orgName></list><tree><noCountry><name sortKey="Alexandrov, Andrei V" sort="Alexandrov, Andrei V" uniqKey="Alexandrov A" first="Andrei V" last="Alexandrov">Andrei V. Alexandrov</name><name sortKey="Goyal, Nitin" sort="Goyal, Nitin" uniqKey="Goyal N" first="Nitin" last="Goyal">Nitin Goyal</name><name sortKey="Tsivgoulis, Georgios" sort="Tsivgoulis, Georgios" uniqKey="Tsivgoulis G" first="Georgios" last="Tsivgoulis">Georgios Tsivgoulis</name><name sortKey="Zand, Ramin" sort="Zand, Ramin" uniqKey="Zand R" first="Ramin" last="Zand">Ramin Zand</name></noCountry><country name="Grèce"><noRegion><name sortKey="Katsanos, Aristeidis H" sort="Katsanos, Aristeidis H" uniqKey="Katsanos A" first="Aristeidis H" last="Katsanos">Aristeidis H. Katsanos</name></noRegion><name sortKey="Safouris, Apostolos" sort="Safouris, Apostolos" uniqKey="Safouris A" first="Apostolos" last="Safouris">Apostolos Safouris</name></country><country name="France"><region name="Île-de-France"><name sortKey="Turc, Guillaume" sort="Turc, Guillaume" uniqKey="Turc G" first="Guillaume" last="Turc">Guillaume Turc</name></region><name sortKey="Cordonnier, Charlotte" sort="Cordonnier, Charlotte" uniqKey="Cordonnier C" first="Charlotte" last="Cordonnier">Charlotte Cordonnier</name><name sortKey="Oppenheim, Catherine" sort="Oppenheim, Catherine" uniqKey="Oppenheim C" first="Catherine" last="Oppenheim">Catherine Oppenheim</name></country><country name="Allemagne"><region name="Berlin"><name sortKey="Nolte, Christian H" sort="Nolte, Christian H" uniqKey="Nolte C" first="Christian H" last="Nolte">Christian H. Nolte</name></region><name sortKey="Fiebach, Jochen B" sort="Fiebach, Jochen B" uniqKey="Fiebach J" first="Jochen B" last="Fiebach">Jochen B. Fiebach</name><name sortKey="Scheitz, Jan F" sort="Scheitz, Jan F" uniqKey="Scheitz J" first="Jan F" last="Scheitz">Jan F. Scheitz</name><name sortKey="Schellinger, Peter D" sort="Schellinger, Peter D" uniqKey="Schellinger P" first="Peter D" last="Schellinger">Peter D. Schellinger</name></country><country name="Suisse"><region name="Canton de Berne"><name sortKey="Jung, Simon" sort="Jung, Simon" uniqKey="Jung S" first="Simon" last="Jung">Simon Jung</name></region><name sortKey="Klinger Gratz, Pascal P" sort="Klinger Gratz, Pascal P" uniqKey="Klinger Gratz P" first="Pascal P" last="Klinger-Gratz">Pascal P. Klinger-Gratz</name><name sortKey="Mattle, Heinrich P" sort="Mattle, Heinrich P" uniqKey="Mattle H" first="Heinrich P" last="Mattle">Heinrich P. Mattle</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Alexandrov, Anne W" sort="Alexandrov, Anne W" uniqKey="Alexandrov A" first="Anne W" last="Alexandrov">Anne W. Alexandrov</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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